Thursday, June 25, 2020

MECHANISM OF ACTION OF HYPERBARIC MEDICINE:


by

Dr Khurrum Shaukat Yusafzai ,
Hyperbaric Medical Consultant.









Click to Watch Video : https://youtu.be/dd_7GvLvvI8



Introduction

  • How Hyperbaric Medicine is able to Treat 300 Diseases ?
  •  This is the Question is on Minds of a lot of People that How Simple HBO Treatment can , be so Powerful and yet Effective ? 
  •  Today Video I will explain Mechanism of Actions of Hyperbaric Medicine, to provide some answers 
I will do that one by one ,  So let's begin

Increases the Body Oxygenation in the Tissues :


Hyperbaric Chamber and Ventilator are both Oxygenator Devices ,
Ventilators are Normobaric System as they act at Sea level known as 1 ATM
Hyperbaric Acts on Greater then Sea Level Pressures which can range up to 4 ATM or more especially When Treating Diving Diseases called Decompression Sickness

Hyperbaric oxygen Difference between the 2 , is that Hyperbaric Chamber Increases Oxygenation via Pressurized Environment while the Ventilator does it via Non Pressured Environment but with Positive Pressure Assisted Breathing .

Hyperbaric Chamber is known as Device that can Load Oxygen in the Body without the Need of Even the RBC /  Blood as it can Load oxygen Directly by Loading it in the Plasma or Body as 70% of that is water.

Hyperbaric Chambers can Treat Diseases and the Ventilators can just do Assisted Ventilation.

Increasing Body Immunity :



Hyperbaric Chambers Increases the Mitochondrial function in the Cells , and of Anti-Bodies are Also cells and its Function is Increased 300 % .

Oxygen acts as an antibiotic by impairing the bacterial metabolism. The effect of HBO is not selective but covers a broad spectrum of gram positive AND Gram negative organisms, It is most effective in anaerobic infections.

HBO produces free radicals which are toxic to the microorganisms. Oxygen has a direct bactericidal or bacteriostatic effect equal to that of some antibiotics especially on Anaerobic Infections .

HBO improves the phagocytosis, which is impaired by hypoxia,

Hypoxia impairs the immune mechanism of the body, whereas HBO improves it.

It Increases Effects of Anti-Biotics , HBO has a synergistic effect on sulfonamides, and increases the effect 5-10 fold effect on Aminoglycosides is reduced in anoxic conditions.

but with Hbot it is effective in Transporting the drug into bacteria and Enhanced Effects is Observed.

HBO inhibits the exotoxin production, in Gas Gangrene

e.g., alpha-toxin of C. perfringens or detoxifies the oxygen-labile exotoxins, e.g., theta-toxin of C. perfringens of Gas Gangrene

HBO is effective in drug resistant infections,

Acts on Cancer Cells and Reduce its Growth as , Normal Human Body also Produce 1500 Cancer Cells daily but Immunity take care of it as eat them to Keep Balance ,

Keeping the Body Healthy , with Increased Immunity via HBOT the Cancer is Stopped from Growing and Multiplying.


IT Decrease the Swelling and Inflammation


Inflammation, one of the most common mechanisms of disease and injury, is caused by biochemical byproducts that are manufactured by the body’s natural immune response.

Hyperbaric oxygen markedly decreases inflammation by stimulating the body’s own anti-inflammatory defenses.

This may be the single most important function of HBOT.
Cytokine Storm and Body Inflammatory Agents damage the Lungs and Other Organs of Body

And Hyperbaric Medicine takes care of that ,Autoimmune Disease are therefore kept in check.

IT Decreases Edema


Water in the Lungs or Edema as Patient is Drowned in his own Secretions

The net increase in arteriolar vasoconstriction and systemic vascular resistance leads to an overall decrease in tissue edema and increased tissue oxygenation.

Although vasoconstriction partially impedes blood flow, the hyperoxygenation of the plasma results in an overall gain in delivered oxygen.

Decreasing Scars and Keloids Formation


It Decreases the Lungs Deformation because of the Scaring because of Injury due to Viral Infections

Angiogenesis:

Hyperbaric Oxygen stimulates the body to grow new capillaries (angiogenesis),

essentially building a new collateral circulatory system to serve injured and healthy tissues alike.

The resulting neovascularization is extremely helpful for reaching tissues and organs that have restricted blood flow (ischemic areas)

as well as areas of the body that are lacking or compromised in available oxygen (hypoxic areas).

Stem Cell Healing Activity :


Non Invasive Method of Increase in Stem Cell Activity is Observed in Hyperbaric Medicine

Hyperbaric Medicine Wound Healing is Observed , because of Stem cell Activity

15 Time Stem Cell Activity is Possible with Hyperbaric Therapy


Epigenetic Therapy


Hyperbaric Medicine has been known to Promote Epi-genetic effects

Any Trait in Body is controlled by 2 or Multiple Sets of Genes
One Set may be responsible for Good Effects and one for the Bad or Un-wanted effects like a Diseases .

Hyperbaric Oxygen Treatment may Lead to , Enhancement of the Good effects to be made Prominent and the Bad Effects to be made Suppressed .


Increased Healing


Overall the Healing Effects is increased because on Increased Mitochondrial effects and Energy from ATP,

The Inflammation and Edema is Reduced,

The Stem Cell Activity is Increased

The Immunity is Increased that Decreased the Microbials

Epigenetic Activity Promotes Good Effects of Genes and Greater Healing

Anti-Ageing Effects :


The DNA is Aged because of Hydrogen Peroxide in Cells that Degrades it and Hyperbaric Oxygen Changes it into water and Oxygen Preventing Ageing

Superoxide Dismutase (SOD) Stimulation – A Surge of Antioxidant Capabilities: Superoxide Dismutase (SOD) is an important enzyme found in human cells

SOD inactivates superoxide's, the most common free radicals in the body, responsible for the destruction of cells and DNA

Hyperbaric Oxygen stimulates SOD production thereby helping the body to rid itself of the by products of inflammation and damaging free radicals

KSYBIZ HYPERBARIC CHANNEL 


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Bye and take care and see you soon,

Thanking you in Anticipation,


From,




Dr. Khurrum Shaukat Yousafzai
Director Chinar Trust Hospital,
Director Ksy Hyperbarics Consultancy,
Founder Hyperbaric Medical Society Pakistan,
Twitter: ksybiz
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1 comment:

  1. Nice blog. This blog clearly shows how HBOT therapy work and help to recover from crush injury and wound healing. I found this information very helpful. Thanks for sharing

    ReplyDelete